Mega Millions Winning Numbers – September 16, 2025

Millions of gamers from all over the United States watched the Mega Millions drawing on Tuesday, September 16, 2025, as usual, filled with excitement over a jackpot that had risen into the hundreds of millions. As is customary, the drawing occurred at 11 p.m. ET, leaving the big time lottery fans representing the "edge of their seat" during the drawn numbers.

Winning Numbers for September 16, 2025

The winning numbers drawn on September 16, 2025 were:

10 – 14 – 34 – 40 – 43
Mega Ball: 5

Every drawing brings anticipation, suspense, and the possibility of a life-changing prize, which is why Mega Millions is among the most anticipated lottery games in the U.S.

Mega Millions Jackpot Update

The published jackpot (the cash amount) for the September 16 drawing was $400 million; however, the official lottery subsequently reported the amount to be closer to $423 million. Winners can claim the jackpot in one of two options:

• Annuity: The winner will receive 29 total payments as part of their jackpot (total repayment = full amount of (advtised) cash option).
• Cash Option: An immediate payment that is lower than the annuity loan, but still a significant amount of the cash option); typically in the hundreds of millions of dollars.

The growing jackpot will ensure the anticipation continues toward the next drawing.

How to Play Mega Millions Lottery

Mega Millions is easy to understand and incredibly exhilarating. Each ticket costs $2, and players select:

• Five white ball numbers between 1-70
• One gold Mega Ball number between 1-25

You win the jackpot by matching all six numbers, and of course, there are nine prize levels altogether. Even if you don't match all the winning numbers there are many chances to win, ranging from $2 to a million or more, so winning small prizes adds excitement even if it is not the jackpot. The optional Megaplier is available for $1 to multiply any non-jackpot prizes up to 5 times! 

Mega Millions Prize Levels and Odds of Winning

Mega Millions isn't just about winning the big jackpot — it also has multiple ways to win! With 9 prize levels, players have lots of chances to win even if they don't match all the numbers.

Here’s a summary of ways to win:

• Match 5 + Mega Ball → Jackpot (starting at $20 million)
• Match 5 → $1,000,000*
• Match 4 + Mega Ball → $10,000*
• Match 3 + Mega Ball → $200
• Match 2 + Mega Ball → $10
• Match 1 + Mega Ball → $4
• Mega Ball only → $2

This tiered prize level system keeps the winners coming and thousands of players win smaller amounts in each draw, which keeps the excitement going even when getting the jackpot isn't a reality.

When Will the Next Mega Millions Draw Happen? 

The next Mega Millions draw will happen on Friday, September 19, 2025, at 11 p.m. ET. Now that the jackpot is valued at around $423 million, it is expected that ticket sales will increase as thousands of players line up for a chance at one of the biggest prizes of the year.

Why Mega Millions Remains Popular

While the massive Mega Millions jackpots are certainly part of the allure there is also a rushing excitement twice a week, the experience of watching the drawing and dreaming of what you would do if you won. At the same time, there are plenty of smaller prizes that reward your investment should you not take home the jackpot.

The price of a ticket makes the game affordable to millions of players. Every time the jackpot gets rolled over, your investment offers the chance at a life-altering event, which usually fuels the dreams of people in every part of the country.