• Published: Jun 04 2025 11:23 AM
  • Last Updated: Jun 04 2025 11:23 AM

A drug-resistant fungus found in China raises global health concerns. Learn how it spreads, resists treatment, and why experts are alarmed.


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Health experts in China have discovered a new fungus that is raising alarms around the world. This fungus, known as Rhodosporidiobolus fluvialis, was found in the blood of two patients treated at hospitals in different cities. Though it was identified years ago, it is only now getting public attention due to its potential to cause infections in humans and its ability to resist common treatments. Scientists are especially concerned about this fungus because it can survive and mutate quickly at the temperature of the human body. This means it could become even more dangerous over time and harder to treat.

Rare Fungus Discovered in Chinese Hospitals

The fungus Rhodosporidiobolus fluvialis was first detected in two unrelated hospital cases—one in Nanjing in 2013 and another in Tianjin in 2016. Both patients were very ill and died while infected with the fungus. Doctors are not yet sure whether the fungus was the direct cause of death, but its presence is enough to worry researchers. What makes this fungus unusual is that it’s never been seen infecting humans before. After further lab testing, scientists found that the fungus was capable of surviving at 37°C, which is the normal temperature of the human body. This makes it more dangerous than many other fungi.

Fungus Shows Strong Drug Resistance

One of the biggest problems with Rhodosporidiobolus fluvialis is that it does not respond well to common antifungal medications. Drugs like fluconazole, amphotericin B, and caspofungin, which are normally used to treat fungal infections, do not work effectively against it. This makes treating patients infected with this fungus more difficult and could result in longer hospital stays or more severe health outcomes. Experts say drug-resistant fungi are a growing global threat, especially in hospitals and among people with weak immune systems. This new fungus adds to the list of dangerous organisms that doctors may soon have to fight without reliable medicines.

Rapid Rise in Candida auris Cases in China

While the new fungus is just starting to be studied, another fungus called Candida auris is already causing serious problems in China. Reports show a sharp rise in Candida auris infections, from 33 cases in 2022 to 182 cases in 2023. This fungus spreads quickly in hospitals and is very hard to eliminate. It can survive on surfaces for long periods and does not respond to many antifungal drugs. Some patients are even infected with more than one type of C. auris at the same time, which makes treatment even harder. Health experts warn that hospitals need stronger infection control systems to stop its spread.

China Develops New Drug to Fight Fungal Infections

To fight the rise of drug-resistant fungi, scientists in China have developed a new antifungal drug called mandimycin. This drug has shown promising results in laboratory tests, especially against Candida auris. Unlike other treatments, mandimycin seems to work even when other medications fail. This breakthrough gives doctors new hope in treating infections that are becoming harder to manage. However, more testing is still needed before it can be used widely. Developing new drugs takes time and must go through safety checks. Still, this new discovery is an important step forward in the fight against fungal infections that don’t respond to current treatments.

Climate Change May Be Making Fungi More Dangerous

Some scientists believe that climate change is playing a big role in the rise of dangerous fungi. As the Earth gets warmer, fungi that were once harmless in nature are now adapting to survive inside human bodies. Normally, many fungi can’t handle body heat, but rising temperatures are forcing them to evolve. This means we could start seeing more fungal infections in the future, especially from new species that were never a problem before. Rhodosporidiobolus fluvialis may be one such example. Experts warn that if we don’t act quickly to understand and manage these threats, they could turn into serious public health issues.

What Can Be Done to Prevent Fungal Outbreaks?

Preventing the spread of dangerous fungi starts with better awareness and stronger safety practices in hospitals. Medical staff need proper training in how to spot and handle fungal infections early. Hospitals should clean and disinfect more often, especially in areas where patients are at higher risk. Public health agencies should invest in research to understand how these fungi spread and how to stop them. Creating new antifungal drugs is also important, as current treatments may not work forever. Finally, climate change must be taken seriously, because warmer temperatures are helping fungi become stronger and more harmful to humans.

Image Source: madrastribune.com

FAQ

It is a newly discovered fungus in China that can infect humans and is resistant to common antifungal drugs.

It was found in blood samples from two patients in hospitals in Nanjing and Tianjin, China.

Most common antifungal medicines don’t work well against it, which is why it's seen as a serious concern.

Candida auris is a fast-spreading fungus that survives in hospitals and resists treatment. Infections are rising in China.

Warming temperatures may help more fungi adapt to live inside the human body, increasing the risk of new infections.

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